How to optimize choice of smart drugs, individually?
Generally, we want to improve our mental abilities, as this is useful for all kind of goals. However, it remains a difficult problem. For example, some smart drugs may decrease longevity (we should have a category for that, too), which reduces the likelyhood of reaching both the technological singularity, and the longevity escape velocity. On the other hand, using smart drugs may increase the mental acuity, that may enable the very breakthroughs needed to overcome problems in general.
The choice of neuro-modulation strategies is broad, each individual is unique, and, by the amount we are taking, food has to count as one of the key elements of that too, as we are playing the "tetris of life", to optimize our organism's metabolic and signaling "shapeflows".
So, the problem is -- how to intelligently choose what and when to eat. When playing tetris -- it is not good to have the same bricks falling all the time, in most cases. An organism benefits from variation of ingested substances over time, to clear the metabolytes, and so, we should vary diet and supplementation, question is -- how?
關於一些細節。我嘗試過多種物質，從長春西汀到拉西坦、普拉西坦、莫達非（我不推薦）、Phenibut、銀杏等。然而，我傾向於只喫維生素和阿司匹林（從營養方面來看，魚油、葡萄柚、大蒜和咖啡）。在礦物質和維生素中，我使用檸檬酸鎂、Triovit（抗氧化劑）、Multi-B Strong（B 族維生素）和 Vitiron 或 Neurozan——作爲廣譜補充劑，並結合一些抗衰老物質，如白藜蘆醇和 NMN （還沒有勇氣開始服用二甲雙胍）。
Regarding some specifics. I had tried multiple substances, from Vinpocetine, to Piracetam, Pramiracetam, Modafinil (which I do not recommend), Phenibut, Ginkgo Biloba, and others. However, I tend to stick with just vitamins and aspirin (+fish oil, grapefruits, garlic, and coffee, from the nutrients side). Among minerals and vitamins, I use Magnesium citrate, Triovit (antioxidants), Multi-B Strong (B-vitamins), and either Vitiron or Neurozan -- for broad spectrum supplements, combined with a few anti-aging substances, like Resveratrol and NMN (did not have courage start with Metformin yet).
I'm not sure if I'm doing it right or wrong, but, I'd be curious to know also about other people's choices.
當我喝酒非常重要時，我服用了硫胺素 B 複合維生素來消除宿醉或阻止宿醉的發生。
現在我服用 Neuromind 和一個單獨的歐米茄 3 素食膠囊。這使我非常警覺，願意做具有挑戰性的事情。
When I drunk alcohol if was very important I took a Thiamine Bcomplex vitamin to remove the hangover or stop it from occurring.
Nowadays I take Neuromind and a separate omega 3 vegan capsule. This causes me to be very alert and open to doing challenging things.
// 當我喝酒很重要時，我服用了硫胺素 B 複合維生素來消除宿醉或阻止宿醉的發生。
我不確定它對宿醉有什麼作用，但我在 14 歲的時候給自己注射了氯化硫胺素。我記得它曾經讓嘴脣發麻。 :) 這更像是一種探索性的事情，而不是其他任何事情。
// When I drunk alcohol if was very important I took a Thiamine Bcomplex vitamin to remove the hangover or stop it from occurring.
I'm not sure how it would work for hangovers, but I had injected myself with Thiamine Chloride as a 14 year old kid. I remember it used to make lips tingle. :) It was more of an exploratory thing rather than anything else.
I guess, I was exploring lucid dreaming at that time, and was trying various supplements to improve lucid dreaming. B6 seem to have an effect.
Nootroflix.com is a fine starting point. Also, track your psychophisical metrics and talk to your physician.
Interesting model. I guess, it doesn't make sense to optimize nootropics for mental performance alone: much more sense is to target those nootropics, that simultaneously are anti-aging drugs. Perhaps, "anti-aging nootropics" would be the right category.